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Colorectal Cancer

Colorectal cancer is the third most common cancer in both men and women in the U.S. Each year, colorectal cancer is diagnosed in roughly 55,000 U.S. men and 57,000 U.S. women.17 Because colorectal cancer is quite treatable when detected early, it is commonly recommended that people 50 years of age or older and those at a high risk for colorectal cancer be screened for the disease. Screening methods include testing for blood in the stool (fecal occult blood test), sigmoidoscopy, and colonoscopy.

Colorectal cancer begins in cells that line the colon. As the cells increase in number, they spread around the colon like a "napkin ring." If not detected early, the cancer may spread into nearby organs throughout the body to the liver, lungs and other organs. In order to understand the best treatment options available for treatment of colorectal cancer, it is important to first determine where the cancer has spread in the body.

Treatment of colorectal cancer varies by stage of the disease.

Stage 0: Carcinoma in situ; cancer is confined to the innermost layer of the colon

Stage I: Cancer extends beyond the innermost layer of the colon.

Stage II: Cancer may get through the wall of the colon into the abdominal cavity or other nearby organs but does not invade any local lymph nodes.

Stage III: Cancer invades one or more of the local lymph nodes but has not spread to distant organs.

Stage IV: Cancer has spread to distant locations in the body, which may include the liver, lungs, bones or other sites.

American Cancer Society: About Staging

Treatment of colorectal cancer may involve surgery, chemotherapy, radiation therapy, or targeted therapy. It is important for patients to remember that treatment is determined by the stage and other specific characteristics of the cancer. Patients should speak with their doctor to discuss the individual risks and benefits of each treatment option.

 

Neulasta® (pegfilgrastim) is prescribed to reduce the risk of infection (initially marked by fever) in patients with some tumors receiving strong chemotherapy that decreases the number of infection-fighting white blood cells.

Important product safety information
Ruptured spleen (including fatal cases), serious allergic reactions, and a serious lung problem called acute respiratory distress syndrome have been reported. Call your doctor or seek emergency care right away if you have abdominal or shoulder tip pain, shortness of breath, trouble breathing, a fast rate of breathing, or any allergic reaction. The most common side effect of this injection is mild to moderate bone pain. If you have any questions about this information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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