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Chemotherapy induced anemia
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Breast Cancer

Breast cancer is the most common cancer in U.S. women, with more than 178,000 new diagnoses each year.17 Breast cancer can also affect men, and there are roughly 2,000 new diagnoses of male breast cancer each year. Survival with breast cancer has improved in recent decades due to a combination of early detection and improvements in treatment.

The suspicion of breast cancer first occurs when a lump is found in the breast during breast examination or a mass found on a mammogram. A physician will perform a biopsy to understand the cause of the breast mass or lump. During a biopsy, a physician removes cells for examination in the laboratory to determine whether cancer is present. Other information obtained from the biopsy sample may play an important role in treatment decisions.

There are many types of breast tumors. Some breast tumors are benign (not cancerous). Benign breast tumors do not spread outside of the breast. Other breast tumors are cancerous. When cancer is identified after a biopsy, several other tests are performed to classify the cancer and to determine the best treatment strategy.

Choice of breast cancer treatment varies by the stage of the cancer:

Stage I: Cancer is confined to a single site in the breast, is less than 2 centimeters (3/4 inch) in size and has not spread outside the breast.

Stage IIA: Cancer has spread to involve underarm lymph nodes and is less than 2 centimeters (3/4 inch) in size or the cancer is 2-5 centimeters (3/4-2 inches) and has not spread to the lymph nodes.

Stage IIB: Cancer is 2-5 centimeters in size and has spread to the underarm lymph nodes or cancer is greater than 5 centimeters in size and does not involve any lymph nodes.

Stage IIIA: Cancer is greater than 5 centimeters and has spread to the underarm lymph nodes, or cancer is any size and involves lymph nodes that are attached to each other or to other structures.

Stage IIIB: Cancer directly involves the chest wall or skin.

Stage IIIC: Cancer has spread to lymph nodes near the neck or collarbone, or to lymph nodes under the arm and near the center of the chest.

Stage IV: Cancer has spread to distant locations in the body, which may include the liver, lungs, bones or other sites.

American Cancer Society: About Staging

Treatment for breast cancer may involve surgery (lumpectomy or mastectomy), radiation therapy, hormonal therapy, chemotherapy, and/or targeted therapy. It is important for patients to remember that treatment is determined by the stage and other specific characteristics of the cancer. Patients should speak with their doctor to discuss the individual risks and benefits of each treatment option.

 

Neulasta® (pegfilgrastim) is prescribed to reduce the risk of infection (initially marked by fever) in patients with some tumors receiving strong chemotherapy that decreases the number of infection-fighting white blood cells.

Important product safety information
Ruptured spleen (including fatal cases), serious allergic reactions, and a serious lung problem called acute respiratory distress syndrome have been reported. Call your doctor or seek emergency care right away if you have abdominal or shoulder tip pain, shortness of breath, trouble breathing, a fast rate of breathing, or any allergic reaction. The most common side effect of this injection is mild to moderate bone pain. If you have any questions about this information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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