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By My Side™ Cancer Treatment Chemotherapy guide
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Find out more about chemotherapy and different side effects associated with chemotherapy...
 
Understanding Your CBC - Complete Blood Count

While you're receiving chemotherapy, your doctor will order tests on a regular basis to check your complete blood count (CBC). Following is a brief explanation of the components of your CBC and the normal values for each:

Normal Lab Values for Complete Blood Count

Erythrocytes
Red blood cells, measured in terms of their number per a specific volume.

— male 4.7 — 6.1 million/mm3
— female 4.2 — 5.4 million/mm3

Hemoglobin
The oxygen-carrying protein of red blood cells, measured in terms of weight.
— male 14 — 18 g/dL
— female 12 — 16 g/dL

Hematocrit
The percentage of the blood made up of red blood cells.
— male 42% — 52%
— female 37% — 47%

Leukocytes 5,000 — 10,000/mm3
White blood cells — the cells that help the body fight infections and disease — are measured in terms of their number per a specific volume. The five specific types of white blood cells that follow are measured as a percentage of all leukocytes (white blood cells):

— Neutrophils 55% — 70%
First line of cellular defense against bacterial infection.

— Lymphocytes 20% — 40%
B cells, which create antibodies against foreign invaders, such as infections and tumor cells, and T cells, which attack the same foreign invaders.

— Monocytes 2% — 8%
Ingest foreign material, such as bacteria and fungi.

— Eosinophils 1% — 4%
Destroy parasites and play a major role in allergic reactions.

— Basophils 0.5% — 1%
Play a major role in inflammation.

Platelets 150,000 — 400,000/mm3
Cells that help stop bleeding by binding to the site of a wound.

Calculating Absolute Neutrophil Count (ANC)

The absolute neutrophil count (ANC), a part of the CBC, is a measure that helps your health care provider assess your body's ability to prevent and fight infections. Below is a brief explanation of how ANC is calculated. A patient's risk of infection begins to increase when the ANC falls below 2,000, with the greatest risk occurring below 500.

Lab values reported in percentages
If total white count = 2,000/mm3
Total segs* = 23% Total bands = 2%  
23%    +
25%    x
Total of
segs & bands
2%    =
2,000    =
Total
white count
25%
500
ANC


Lab values reported in total numbers
Total segs* = 0.4 Total bands = 0.1  
0.4    +
0.5    x
.1    =
1,000    =
0.5
500
*Segs may also be referred to as neutrophils or granulocytes.


Be sure to ask your doctor

  • How often should I get my CBC tested?
  • When should my CBC be tested?
  • What is my ANC?
  • Is my ANC low?
  • What should I do if my ANC is low?
  • Is there anything I can do to protect myself from infection because of a low ANC count?




  •  

    Neulasta® (pegfilgrastim) is prescribed to reduce the risk of infection (initially marked by fever) in patients with some tumors receiving strong chemotherapy that decreases the number of infection-fighting white blood cells.

    Important product safety information
    Ruptured spleen (including fatal cases), serious allergic reactions, and a serious lung problem called acute respiratory distress syndrome have been reported. Call your doctor or seek emergency care right away if you have abdominal or shoulder tip pain, shortness of breath, trouble breathing, a fast rate of breathing, or any allergic reaction. The most common side effect of this injection is mild to moderate bone pain. If you have any questions about this information, be sure to discuss them with your doctor. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

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